1、線上報(bào)告
報(bào)告一
報(bào)告題目：Introduction into structural biochemistry. The levels of protein structure. History of structural biology. X-ray analysis. Soluble and membrane proteins, crystallization difficulties. The beginning of the development of electron microscopy.
時(shí)間：2024年11月12日（周二），9:00-11:00
報(bào)告二
報(bào)告題目：The possibilities and application of electron microscopy in plant biology, the foundations of structural proteomics, comparison with other methods. Transmission electron microscope device. Diagram of the microcope. Different types of cathodes and lenses. Condenser. Stage. Vacuum system.
時(shí)間：2024年11月14日（周四），9:00-11:00
報(bào)告三
報(bào)告題目：Three-dimensional reconstruction: basic principles. Two-dimensional projections as the basis for a three-dimensional image. Two-dimensional and three-dimensional Fourier transform. Euler Sphere. Methods for constructing three-dimensional reconstruction: angular reconstitution, projection matching. Definition of permission for reconstruction; Factors affecting the reconstruction. Heterogeneity of particles. Three-dimensional classification.
時(shí)間：2024年11月26日（周二），18:30-20:30
報(bào)告四
報(bào)告題目：Structure of globular proteins. Protein domains consisting of alpha helices and beta sheets; Dps, albabetin, Ribosome; molecular basis of protein biosynthesis; protein folding; chaperonins, molecular basis of transcription; structures of polymerase and histones; chromatin remodeling factors
時(shí)間：2024年11月28日（周四），18:30-20:30
報(bào)告五
報(bào)告題目：Structure of fibrillar proteins. Cytoskeleton. Microtubules. Actin activators, inhibitors and bundlers. Formins, Arp2/3 complex. Mechanical strength.
時(shí)間：2024年12月3日（周二），18:30-20:30
報(bào)告六
報(bào)告題目：Purification of membrane proteins. Structure of membrane proteins. Ion channels; activation mechanisms, ligand-dependent channels: KATP channels link metabolism to electrical activity; Functional roles of ion channels, aquaporins; transporters, mechanosensitive channels; Transporters; differences between transporters and ion channels.
時(shí)間：2024年12月5日（周四），18:30-20:30
報(bào)告七
報(bào)告題目：Structure of photosynthetic apparatus. Proteins involved into photosynthesis. Light-harvesting complexes, Phycobilisomes.
時(shí)間：2024年12月10日（周二），18:30-20:30
報(bào)告八
報(bào)告題目：Structure of plant and bacterial viruses. DNA- and RNA-containing viruses; high-resolution structure acquisition; bacteriophages; different types of symmetry, difference between plant, bacterial and animal virues.
時(shí)間：2024年12月12日（周一），18:30-20:30
方式：通過騰訊會(huì)議遠(yuǎn)程視頻講座，鏈接https://meeting.tencent.com/dm/aLOnCz1hAAAI
騰訊會(huì)議：741-8361-4777
會(huì)議密碼：150040
2、線下報(bào)告
報(bào)告一
報(bào)告題目：The similarity and difference of light and electron microscopes. Image formation, electron scattering by a sample; Methods for obtaining and registering images. Direct electron detectors. Preparation of samples for TEM. Ultrasections. Cryo substitution. Grids for samples. Negative contrast. Cryo microscopy.
時(shí)間：2024年11月19日（周二），9:00-11:00
報(bào)告二
報(bào)告題目：History of single particle EM. Particle collection: manual and semi-automatic; A review of particle collection programs. Primary processing of electron microscopic images. Image quality. Classification of electron microscopic images. Signal to noise ratio. Analysis factors; Particle alignment; Basics of multivariate statistical analysis. Hierarchical classification; Multi-reference classification. Permission and criteria for its evaluation. Radiation damage. Focus; Aberrations and their effect on image quality. Contrast. Ways to increase contrast.
時(shí)間：2024年11月20日（周三），9:00-11:00
地點(diǎn)：東北林業(yè)大學(xué)逸夫?qū)嶒?yàn)樓315會(huì)議室
報(bào)告人：Sokolova Olga教授，深圳北理莫斯科大學(xué)教授
報(bào)告人簡(jiǎn)介：
Sokolova Olga教授于1987年在皮洛耶夫醫(yī)學(xué)院獲得學(xué)士學(xué)位，并分別于1996年和2012年先后獲得生理學(xué)和生物物理學(xué)博士，自2020年后任深圳北理莫斯科大學(xué)教授。她的科研方向包括生物物理學(xué)、結(jié)構(gòu)生物學(xué)、納米生物技術(shù)及冷凍電鏡的應(yīng)用。Sokolova Olga教授曾獲簡(jiǎn)·科芬查爾茲和奧格龍博士后獎(jiǎng)學(xué)金，MSU發(fā)展計(jì)劃競(jìng)賽一等獎(jiǎng)等諸多獎(jiǎng)勵(lì)。近十年來，Sokolova Olga教授在PNAS，Nature communications，Biomedicines，Communications Biology等高水平期刊發(fā)表諸多研究成果。
歡迎各位老師和同學(xué)積極參加!
